A study on autologous non-cultured melanocyte transfer in patients of stable vitiligo at a tertiary care centre

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Original Article

Author Details : Meetesh Agrawal, Krishnendra Varma, Ujjwal Kumar, Shashank Bhargava, Shaily Gupta*

Volume : 9, Issue : 2, Year : 2023

Article Page : 61-65

https://doi.org/10.18231/j.ijced.2023.011

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Abstract

Background: Vitiligo is an acquired pigmentary disorder caused due to a loss of functional melanocytes. Autologous non-cultured melanocyte transfer (NCMT) is a recent surgical modality for the treatment of stable vitiligo.
Objective: To evaluate the clinical outcome of NCMT in patients of stable vitiligo.
Materials and Methods: Autologous melanocyte transfer was performed on 41 patients of stable vitiligo. They were evaluated at 1, 4, 12, 18 and 24 weeks post-surgery for extent for repigmentation and complications.
Results: In this study, the male- female ratio was nearly equal, with 51% males and 48% females the mean duration of stability of vitiligo lesion was 3.39 years. By 24 week of follow-up, 56.09% had excellent repigmentation (>90%), while 31.70% patients had good pigmentation (75-90%). No significant complications in donor area or recipient site were noted.
Conclusion: Autologous non-cultured melanocyte transfer is a quick, single day procedure, and can be performed on an out-patient basis. It requires lesser technicalities than other surgical procedures for treating vitiligo and can prove to be an effective treatment modality in achieving homogenous repigmentation with an excellent degree of patient satisfaction.
 

Keywords: Non-cultured melanocyte transfer, Vitiligo

How to cite : Agrawal M, Varma K, Kumar U, Bhargava S, Gupta S, A study on autologous non-cultured melanocyte transfer in patients of stable vitiligo at a tertiary care centre. IP Indian J Clin Exp Dermatol 2023;9(2):61-65

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