A case series of sweet syndrome like erythema nodosum leprosum at tertiary care centrein Western India

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Case Series

Author Details : Anandi Gadhe*, Jay Dhirajlal Modha, Bharti K Patel, Neela V Bhuptani

Volume : 10, Issue : 2, Year : 2024

Article Page : 229-234

https://doi.org/10.18231/j.ijced.2024.041

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Abstract

Leprosy is a chronic disease caused by Mycobacterium Leprae, mainly affecting skin and nerves. Chronic course of leprosy may be interrupted by acute inflammatory conditions called lepra reactions. Type 2 reaction (Erythema Nododsum Leprosum/ENL) classically presents as crops of multiple tender, evanescent nodules. Several pleomorphic variants of ENL has been described in the literature such as erythema necroticans, sweet syndrome–like, erythema multiforme like, livedoreticularis like and bullous ENL. Identification of unusual cutaneous features of ENL are of paramount importance ,which poses a diagnostic challenge. The study aimed at identifying the sweet syndrome like ENL, their clinical and histopathological feautures. This is a retrospective study done at a tertiary care centre of western India. There were eight cases of sweet syndrome like ENL. Out of 8 patients, 6 had lepromatous leprosy, 1 each of borderline lepromatous leprosy and histoid leprosy. All patients had a sudden onset of painful erythematous oedematous plaques and nodules with pseudovesiculation. The study emphasizes the importance of early diagnosis and prompt treatment of atypical ENL reactions. WHO Global Leprosy strategy 2030 also emphasizes on early detection to prevent deformities and disabilities, and thereby improving the quality of life of the patients living with the leprosy.
 

Keywords: Sweet syndrome, Lepra Reactions, Erythema nodosum leprosum

How to cite : Gadhe A, Modha J D, Patel B K, Bhuptani N V, A case series of sweet syndrome like erythema nodosum leprosum at tertiary care centrein Western India. IP Indian J Clin Exp Dermatol 2024;10(2):229-234

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