Fixed drug eruption to cetirizine – role of patch testing

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Case Report

Author Details : Sonia Raghukumar, Ravikumar BC

Volume : 2, Issue : 3, Year : 2016

Article Page : 122-124

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Abstract

Antihistamines are prescribed for a wide variety of disorders like urticaria, eczema, allergies and infestations. Adverse reactions due to them is unusual and the incidence of fixed drug eruption is scarce. They are characterized by a sudden onset of edematous, erythematous plaques appearing at the same sites following an oral provocation with the drug and is proposed to be due to the epidermal CD8⁺ T cells resident at the sites of these residual post inflammatory hyper pigmented macules. Antihistamines sharing a similar chemical structure have an increased likelihood of showing cross reactions and a patch test based evaluation can be carried out to deduce the offending drugs, cross reactions and alternative medications.

Keywords: Antihistamines, Fixed drug eruptions, Patch testing

How to cite : Raghukumar S, Ravikumar Bc, Fixed drug eruption to cetirizine – role of patch testing. IP Indian J Clin Exp Dermatol 2016;2(3):122-124

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