A comparative study of efficacy and safety of 5% topical minoxidil with platelet rich plasma versus platelet rich plasma as a monotherapy in male patients with androgenetic alopecia

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Original Article

Author Details : Prashanth R. Kamath, Saumya Goel, Ashok Menon, Amita Murali Babu, Hafsa Eram

Volume : 4, Issue : 3, Year : 2018

Article Page : 241-245

https://doi.org/10.18231/2581-4729.2018.0051

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Abstract

Introduction: Male baldness is genetically determined, most common gradually progressive hair disorder leading to miniaturization of hair follicles. Various modalities have been used in various studies without significant results.
Objective: The aim was to study and compare the two modalities of treatment and to evaluate their results.
Materials and Methods: This is prospective, comparative study. Sample size was 40, twenty in each group. Group 1 was given 5% topical minoxidil solution two times in a day till six months and platelet rich plasma (PRP), Group 2 was given only PRP at three weekly interval for six months. Parameters evaluated before starting, after three months and after six months for - Hair pull test, anagen/telogen ratio, Patient’s, Physician’s assessment and clinical photographs.
Results: On evaluating group 1 showed relatively more significant improvement. On hair pull test significant reduction of hair breakage in group 1. Anagen/telogen ratio showed 8.9 ± 0.3% improvement in anagen hair in group 1 while 5.9 ± 0.5% was in group 2. Improvement was seen in patients of group 1 more than patients of group 2 based on patient’s assessment and photographs.
Conclusion: 5% minoxidil when given with platelet rich plasma was superior and better when compared to platelet rich plasma alone.

Keywords: AGA, PRP, Minoxidil.

How to cite : Kamath P R, Goel S, Menon A, Babu A M, Eram H, A comparative study of efficacy and safety of 5% topical minoxidil with platelet rich plasma versus platelet rich plasma as a monotherapy in male patients with androgenetic alopecia. IP Indian J Clin Exp Dermatol 2018;4(3):241-245

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