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- DOI 10.18231/j.ijced.95100.1758882943
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Unmasking the error: Syringocystadenoma papilliferum mistaken for squamous cell carcinoma
Syringocystadenoma Papilliferum (SCAP) is a rare benign adnexal tumor. We report a rare case of Syringocystadenoma Papilliferum (SCAP) in a 20-year-old male, initially misdiagnosed as Squamous Cell Carcinoma (SCC) based on clinical history, atypical site of the lesion, examination and family history of breast carcinoma. However, histopathological examination revealed typical features of SCAP, thus, emphasizing the critical role of histopathology in distinguishing benign conditions from malignancies and avoiding unnecessary intervention. It also highlights a potential molecular link involving the MAPK pathway, shared between SCAP and breast carcinoma, warranting further research.
References
- Chauhan A, Gupta L, Gautam RK, Bhardwaj M, Gopichandani K. Linear syringocystadenoma papilliferum: a case report with review of literature. Indian J Dermatol. 2013;58(5):409.
- Candrawinata VS, Koerniawan HS, Prasetiyo PD, Baskoro BA. Syringocystadenoma papilliferum in a 20-year-old adult: a case report and literature review. J Surg Case Rep. 2022;2022(10):470.
- Sangma MM, Dasiah SD, Bhat VR. Syringocystadenoma papilliferum of the scalp in an adult male - A case report. J Clin Diagn Res. 2013;7(4):742–3.
- Chauhan P, Chauhan RK, Upadhyaya A, Kishore S. Dermoscopy of a rare case of linear syringocystadenoma papilliferum with review of the literature. Dermatol Pract Concept. 2018;8(1):33–8.
- Alhumidi AA. Simple approach to histological diagnosis of common skin adnexal tumors. Pathol Lab Med Int. 2017;9:37–47.
- Lee KG, Choi W, Lim JS, Hahn HJ, Myung KB, Cheong SH. Syringocystadenocarcinoma papilliferum: a case report and review of the literature. Ann Dermatol. 2019;31(5):559–62.
- Marvalim C, Datta A, Lee SC. Role of p53 in breast cancer progression: an insight into p53 targeted therapy. Theranostics. 2023 Feb 27;13(4):1421–42.
- Griffiths C, Barker J, Bleiker T, Chalmers R, Creamer D, editors. Rook's textbook of dermatology. 10th ed. Hoboken (NJ): Wiley- Blackwell; 2022.
- Chilamakuri R, Agarwal S. Direct targeting of the Raf-MEK-ERK signaling cascade inhibits neuroblastoma growth. Curr Oncol. 2022;29(9):6508–22.
- Halsey JN, Faith EF, Logan SJ, Shenoy A, Schieffer KM, Cottrell CE, et al. Syringocystadenocarcinoma papilliferum in a fifteen- year-old girl: a case report and review of the literature. Case Rep Dermatol Med. 2022;2022:8076649.
How to Cite This Article
Vancouver
Rathore A, Bansal K, Tyagi H, Goel S, Mittal S. Unmasking the error: Syringocystadenoma papilliferum mistaken for squamous cell carcinoma [Internet]. IP Indian J Clin Exp Dermatol. 2025 [cited 2025 Oct 02];11(3):418-420. Available from: https://doi.org/10.18231/j.ijced.95100.1758882943
APA
Rathore, A., Bansal, K., Tyagi, H., Goel, S., Mittal, S. (2025). Unmasking the error: Syringocystadenoma papilliferum mistaken for squamous cell carcinoma. IP Indian J Clin Exp Dermatol, 11(3), 418-420. https://doi.org/10.18231/j.ijced.95100.1758882943
MLA
Rathore, Anmol, Bansal, Kritika, Tyagi, Harsh, Goel, Shitij, Mittal, Salony. "Unmasking the error: Syringocystadenoma papilliferum mistaken for squamous cell carcinoma." IP Indian J Clin Exp Dermatol, vol. 11, no. 3, 2025, pp. 418-420. https://doi.org/10.18231/j.ijced.95100.1758882943
Chicago
Rathore, A., Bansal, K., Tyagi, H., Goel, S., Mittal, S.. "Unmasking the error: Syringocystadenoma papilliferum mistaken for squamous cell carcinoma." IP Indian J Clin Exp Dermatol 11, no. 3 (2025): 418-420. https://doi.org/10.18231/j.ijced.95100.1758882943