IP Indian Journal of Clinical and Experimental Dermatology

Official Publication of Khyati Education and Research Foundation


Volume 11, Issue 2, Year 2025
Editor Desk
From the Editor’s Desk
Author details: Rita Vora
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Review Article
Anesthesia in Dermatological Practice: A short review
Author details: Balakumaran Chandrasekaran, Geo Celestin Danny, Ashok Kumar, Sukanya Gurusamy, Sakthi Megalai
Dermatologists are extensively using anesthetics to provide analgesia in dermatologic and laser procedures. The purpose of this review article is to provide some insight on the anesthesia and anaesthetic medications already in use in dermatological practice along with the newer modalities in anesthe....
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A review on grafting new ways in the management of chronic leg ulcers on an outpatient basis
Author details: Gayathri Sreekumar, Shreya Srinivasan, Vignesh Nambi Ravi, Manoharan Dhanaraj, Narayanan Baskaran
Chronic leg ulcer is a common condition leading to clinical concern. Accurate diagnosis and planning treatment are essential components of good management of wellbeing of the patient. Venous and arterial disorders comprise major aetiology of ulceration. Diabetes, hypertension, metabolic disorders, v....
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Original Article
Physician perspectives on the use of glycolic acid, salicylic acid, and urea combination in dermatology practice in Indian settings
Author details: S Manjula, Krishna Kumar M
Background: Keratolytic substances including alpha-hydroxy acids (AHAs), salicylic acid, and urea have long been employed in treating hyperkeratosis and related disorders. Although there were clinical studies available, there was a dearth of studies regarding their clinical practice among clinicians....
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To evaluate role of combination peel (15% TCA and 8% Phenol) in superficial nail plate abnormalities
Author details: Noopur Jain, Jeet Gandhi, Raj Patolia
Background: Superficial nail abnormalities, including conditions like nail psoriasis, idiopathic trachyonychia, and nail lichen planus, present significant therapeutic challenges leading to cosmetic concerns. Aims & Objectives: To evaluate the efficacy of medium depth chemical peel, specifically a t....
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Elevated TNF-alpha and its metabolic implications in psoriasis patients
Author details: Sada Abdul-Ridha, Nazar S. Haddad, Hadaf A. Aljunaiyeh
Background: Psoriasis is a chronic inflammatory skin disease linked to excessive production of tumor necrosis factor-alpha (TNF-?), a cytokine that plays a crucial role in disease development. TNF-? stimulates inflammation and accelerates skin cell proliferation, leading to psoriatic plaque formatio....
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An analysis of various patterns and presentations of oral lichen planus: A clinico epidemiological study
Author details: Raj Patolia, N S Bhavani
Background: Oral Lichen Planus (OLP) is a chronic inflammatory mucocutaneous disorder with varied presentation. Some forms have even been predisposed to malignant potential. Aims & Objectives: To investigate the clinico-epidemiological profile of oral lichen planus and to evaluate various risk facto....
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A study of clinicoepidemiological profile and trichoscopic features in clinical patterns of female pattern hair loss in a rural tertiary care hospital
Author details: Shubhashree Panigrahi, Mukunda Ranga Swaroop, Yogesh Devaraj, Namratha Govindaraju, Richin Anna Johnson, Greeshma Jagadish, Karthick Koravanagundhi Shantha Kumar
Introduction: Female pattern hair loss (FPHL) involves gradual thinning in the frontal, central, and parietal scalp regions and is linked to significant psychological distress. Despite its high prevalence, data on FPHL in the Indian population is limited. Dermoscopy, being a noninvasive diagnostic t....
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Comparative study of platelet rich plasma therapy versus microneedling as a treatment modality for androgenetic alopecia
Author details: Sarthak Bansal, Sanjeev B Gupta, Aayush Gupta, Asharbh Raman, Jahanvi Goyal
Aim: To compare the therapeutic efficacy of platelet-rich plasma (PRP) therapy and microneedling in the treatment of androgenetic alopecia (AGA). Study Design: This analytical cohort study was conducted over an 18-month period, involving 40 male participants with Hamilton-Norwood grades II–IV AGA. M....
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A clinicopathological and immunofluorescence study of immunobullous disorders
Author details: Sowmyashree Krishna, Anusree V Sreedharan, Kikkeri N Naveen, Aditya Agnihotri, Sweta R Prabhu
Aim and Objective: The aim of the study was to evaluate the clinicodemographic profile, histopathology and DIF findings of patients with immunobullous disorders to facilitate diagnostic accuracy and optimal treatment. Background: Immunobullous disorders are blistering disorders in which autoantibodi....
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Dermoscopic evaluation of psoriasis and its association with clinical and histopathological features – A cross-sectional analytical study
Author details: Sheron Christin Armel, Trishna Vaishali, Manjiri Phansalkar
Background: Limited data on the effectiveness of dermoscopy in diagnosing psoriasis. Aim and objectives: To document the dermoscopic findings and to determine the association between clinical, dermoscopic and histopathological features in psoriasis. Materials and Methods: It is a hospital based cros....
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Utility of Direct Immunofluorescence in diagnosis of non – infectious / immune mediated diseases involving skin – Tertiary center
Author details: Mahak Jain, Amit Varma, Gaurav Sharad Pawar, Garima Malpani
Background:  Skin biopsy in Auto immune bullous and other immune mediated disorders are valuable for diagnosis but and additional test which may lead to get a better understanding of the disease likewise DIF and Indirect  immunofluorescence could help clinicians as well pathologist to access more. T....
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Decoding vitiligo: A review of demography, clinical features and associations at a tertiary care hospital in western Gujarat
Author details: Jaskanwal Kaur, Bhavesh Sonagara, Vaishali Makwana, Jubeen Shah, Aditi Arora
Introduction: Vitiligo is a potentially harmless autoimmune skin condition causing white geographic patterns. It is a social taboo especially in India since ancient times. Vitiligo decreases the matrimonial prospects of the affected individuals. There is a variance in prevalence of vitiligo in diffe....
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A study of knowledge and attitude about leprosy among nursing students and nursing staff at a tertiary care health centre in Gujarat
Author details: Rita Vora, Devna S Pillai, Kishan Jadav, Shree Dhanani
Background: Leprosy caused by Mycobacterium leprae, is a infectious disease that remains prevalent in India. The disease carries heavy stigma, leading to social and psychological issues like depression. While medical research on leprosy is extensive, its social aspects remain underexplored. Nursing....
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Comparative evaluation of therapeutic efficacy and safety of apremilast versus cyclosporine in psoriasis vulgaris
Author details: Anjugam Alagappan, Balaguru Natarajan, Balvinder Kaur Brar, Sumir Kumar, Amarbir Singh Boparai
Background: Psoriasis is a chronic relapsing inflammatory skin condition with various treatment options, but achieving significant lesion clearance with minimal side effects remains challenging. Aims: To compare efficacy and safety of Apremilast and Cyclosporine in the treatment of chronic plaque ps....
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An observational study on serum IgE levels in patients with atopic dermatitis
Author details: Bhojani Amee Maganbhai, Priyanshi Dangi, Anitta Elsa Oomman, Kiran V Godse, Sharmila Patil, Anant Patil
Introduction: Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by pruritus, erythema, and recurrent flares, affecting nearly 20% of children and 3% of adults. The disease manifests as extrinsic (IgE-associated) or intrinsic (non-IgE-associated) AD, with IgE playing a cent....
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Clinicomycological study of dermatophytosis in adults at rural tertiary care hospital: A cross- sectional study
Author details: Namratha Govindaraju, Mukunda Ranga Swaroop, Yogesh Devaraj, Richin Anna Johnson, Shubhashree Panigrahi, Shubhashree Panigrahi, Greeshma Jagadish, J Harshini, Balijepalli Sai Vamsi
Background: Dermatophytosis is a common fungal infection affecting skin, hair, and nails, is a significant public health concern in India, with a rising trend of recurrent, recalcitrant, and chronic cases. Despite its high prevalence, dermatophytosis remains a neglected disease, with limited underst....
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Patch testing in suspected cosmetic-induced facial dermatosis: A tertiary care hospital-based prospective, observational study
Author details: Kallolinee Samal, Liza Mohaptra, Nibedita Dixit, Smaranika Satapathy, Anita Subudhi, Dinesh Ranjan Panda
Introduction:  Patch testing is a valuable tool for determining the culprit allergens—chemical combinations of different ingredients, and confirming the existence of an allergy. Studies on patch testing using cosmetic and standard battery series are scarce in the Indian subcontinent. In this study,....
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A swab culture cross-sectional study for confirming the clinical diagnosis of vaginal discharge
Author details: Rachana Patel, Rinkal Suryakantbhai Santoki, Nidhi Mihirkumar Bhalodia, Saurabh Chhotalal Norris, Tanuja Javadekar
Background: Vaginal discharge is a common clinical problem among people of reproductive age. Trichomonas, Candidal vulvovaginitis, and Gardnerella (BV) are the most frequent causes of this underappreciated health problem. Aim: The purpose of the current vaginal swab investigation was to determine th....
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Case Report
Generalized papular rash as a rare sentinel sign of pediatric lupus: Hyper-IgE in a 13-year-old girl
Author details: Natalia Erica Jahja, Zahrah Hikmah, Willy Sandhika, Anang Endaryanto
Systemic lupus erythematosus (SLE) is an autoimmune disorder with diverse dermatologic manifestations. This case report describes a 13-year-old Indonesian girl presenting with generalized erythematous papules, a rare cutaneous sentinel of pediatric SLE. Despite markedly elevated immunoglobulin E (Ig....
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Scleredema adultorum of buschke: An overlooked dermal complication of diabetes
Author details: Yogindher Singh
Scleredema diabeticorum is a rare skin disorder characterized by the stiffening and hardening of subcutaneous tissues on the upper back and posterior neck. Patients with this condition typically experience pain and stiffness in the neck. Here, we present a case of a 47-year-old female with type 2 di....
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Meropenem induced symmetric drug-related intertriginous flexural exanthem
Author details: Samuel Jeyaraj Daniel, Balaji Ganesh Jayaraman, Saranya Selvam, Abirami Thangaraj
Danish dermatologists first identified the baboon syndrome in 1984, referring to a skin eruption that was restricted to the buttocks, axilla, groin and that might have involved the flexural areas and intertriginous zones without systemic involvement. Swiss dermatologists introduced a new acronym, Sy....
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A case of fungal melanonychia in an immunocompetent individual due to dematiaceous fungi
Author details: Jyoti Sharma, Manjula Mehta, Sonia Bhonchal Bhardwaj, Sukhwinder Singh
Dematiaceous fungi, often found in soil and organic debris from both animals and plants, are known to cause cutaneous and subcutaneous infections, particularly in immunocompromised individuals. Although typically saprophytic and considered laboratory contaminants, these fungi can also infect healthy....
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Acenocoumarol induced ecchymosis and multidermatomal haemorrhagic herpes zoster
Author details: Samuel Jeyaraj Daniel, Saranya Selvam, K Desingh
A 65-year-old male presented with haemorrhagic skin lesions over the right buttock region and thighs for the past five days. He also had multiple ecchymotic patches of variable size in the body. Patient gave an history of surgery one month before the onset of haemorrhagic lesions, left iliac vein an....
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Case Series
Exploring reticulate pigmentary disorders - A case series highlighting 5 distinctive types
Author details: Devaraj Yogesh, Richin Anna Johnson, Shubhashree Panigrahi, Harshitha K Reddy, Ron Thomas, Karthick Korvanagundhi Shantha Kumar, Namratha Govindaraju, Jayaprakash Hosmani1
The term "reticulate pigmentary disorders" is used in a broad sense to refer to a heterogenous group of acquired and congenital dermatosis because of their clinical pattern of presentation. Presentations range from the "freckle-like" hyper- and hypopigmented macules that are typically only seen in t....
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