A study of efficacy and safety of newer chemical peels for acne vulgaris grade 1 to grade 3

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Original Article

Author Details : Umesh Karia, Mehul Parghi, Bela Padhiar*, Bela Shah

Volume : 8, Issue : 3, Year : 2022

Article Page : 180-185

https://doi.org/10.18231/j.ijced.2022.037

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Abstract

Background: Acne is a common and complex and multifactorial skin disease that affects individuals of all ages. It commonly presents as Seborrhoea and formation of comedones, papules and pustules. Aim of our study is to evaluate various new chemical peeling agent for search of treatment which stand out with maximum efficacy and least side effect.
Materials and Methods: A total 120 patients were included in our study. Grading of acne was done according to Pillsbury classification and divided into five Treatment groups: Group A: Azelaic peel (20% Azelaic acid peel) Group B: Black peel (8% Acetic acid peel) Group C: Kojic acid peel (12% kojic acid peel) Group D: Lactic acid peel (90% lactic acid peel) Group E: Mandelic acid peel (35% mandelic acid peel). Patients in each arm were subjected to respective chemical peels at an interval of 15 days for a total of 6 sessions. Last visit was done at 12th week. Evaluation done by dermatological examination for acne including counting the number of comedones, papules and pustules.
Results: Patients with improvement at the end of 12 weeks the overall reduction rate was 60.4%, 72.4%, 24.1%, 35.2% and 50.1% with Azelaic peel, Black peel, Kojic acid peel, Lactic acid peel and Mandelic acid peel respectively.
Conclusion: Our study thus concluded that the efficacy of Black peel is highest in the treatment of acne vulgaris grade I to III in Indian patients. The resolution was also observed good with Azelaic acid and Mandelic acid while response was not up to the mark by Lactic acid and Kojic acid peel. However, immediate erythema and burning sensations were more common side effects with black peel. Though the side effects observed with these peels reduced by itself, application of emollients, mild steroids and sun screeners hastened the recovery.

Keywords: Azelaic acid peel, Black peel, Kojic acid peel, lactic acid peel, Mandelic acid peel

How to cite : Karia U, Parghi M, Padhiar B, Shah B, A study of efficacy and safety of newer chemical peels for acne vulgaris grade 1 to grade 3. IP Indian J Clin Exp Dermatol 2022;8(3):180-185

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